INT295100

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 1.09
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pou1f1) DNA binding (Pou1f1) transcription factor binding (Pou1f1)
cytoplasm (Pou1f1)
Anatomy Link Frequency
livers 4
Pou1f1 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 14 51.84 Quite High
anesthesia 7 5.00 Very Low Very Low Very Low
isoflurane 7 5.00 Very Low Very Low Very Low
Osteoarthritis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 98 97.64 Very High Very High Very High
Anaemia 98 87.80 High High
Death 35 86.32 High High
Embryonic Lethality 56 85.52 High High
Hematological Disease 14 85.16 High High
Hemorrhage 14 51.84 Quite High
Splenomegaly 7 31.68 Quite Low
Hemolytic Anemia 7 25.96 Quite Low
Congenital Anomalies 28 21.84 Low Low
Calcification 42 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although further experiments are necessary, this observation could be consistent with a higher expression of PiT1 in developing versus adult fetal livers and the low proliferation rate of PiT1?
Positive_regulation (consistent) of Gene_expression (expression) of PiT1 in livers
1) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.08 Pain Relevance 0
5 MEFs was abolished, this was associated with a 1.8-fold overexpression of PiT2 mRNA (Fig. 8C), which could account for the maintenance of normal Na+-Pi transport in PiT1-null MEFs.
Positive_regulation (overexpression) of Gene_expression (overexpression) of PiT1
2) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.06 Pain Relevance 0
While real-time RT-PCR confirmed that PiT1 expression in PiT1?
Positive_regulation (confirmed) of Gene_expression (expression) of PiT1
3) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.06 Pain Relevance 0
5 mice express functional PiT1 levels that are intermediate between the PiT1?
Positive_regulation (functional) of Gene_expression (levels) of PiT1
4) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.14 Pain Relevance 0.03
While real-time RT-PCR confirmed that PiT1 expression in PiT1?
Positive_regulation (confirmed) of Gene_expression (expression) of PiT1
5) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.06 Pain Relevance 0
Although further experiments are necessary, this observation could be consistent with a higher expression of PiT1 in developing versus adult fetal livers and the low proliferation rate of PiT1?
Positive_regulation (higher) of Gene_expression (expression) of PiT1 in livers
6) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.08 Pain Relevance 0
Animals carrying two copies of hypomorphic PiT1 alleles (resulting in 15% PiT1 expression comparing to wild-type animals) survive at birth but are growth-retarded and anemic.
Positive_regulation (resulting) of Gene_expression (expression) of PiT1
7) Confidence 0.46 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2818845 Disease Relevance 0.61 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox