INT295107

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cilium (Grxcr1) molecular_function (Grxcr1)
Anatomy Link Frequency
smooth muscle cells 2
Grxcr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 1 87.72 High High
cva 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Calcification 6 95.20 Very High Very High Very High
Osteoarthritis 1 87.72 High High
Osteoporosis 5 71.68 Quite High
Anaemia 14 5.00 Very Low Very Low Very Low
Apoptosis 14 5.00 Very Low Very Low Very Low
Embryonic Lethality 8 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low
Hemorrhage 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Particularly, inhibition of Pi uptake by PiT1 small hairpin RNA in cultured vascular smooth muscle cells (VSMCs) blocked the expression of Pi-induced osteogenic differentiation markers, Runx2 and osteopontin, indicating that PiT1 might be a major mechanism for controlling vascular calcification and VSMC phenotypic state [18], [19].
Negative_regulation (blocked) of Gene_expression (expression) of Pi in smooth muscle cells associated with calcification
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2818845 Disease Relevance 0.49 Pain Relevance 0.04

General Comments

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