INT295198

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tlr4, Ptger2) signal transduction (Tlr4) intracellular (Tlr4)
signal transducer activity (Ptger2) cytoplasm (Tlr4)
Tlr4 (Mus musculus)
Ptger2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 16 92.24 High High
antagonist 12 87.04 High High
cytokine 5 82.52 Quite High
monoamine 1 80.48 Quite High
Inflammation 8 74.56 Quite High
Neurotransmitter 2 73.36 Quite High
metalloproteinase 5 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Clonidine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 74.56 Quite High
Neurodegenerative Disease 2 71.52 Quite High
Disease 13 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 1 5.00 Very Low Very Low Very Low
Amyloid Plaque 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Norepinephrine strongly enhanced COX-2 expression and PGE2 production induced by lipopolysaccharide (LPS).
LPS Positive_regulation (induced) of Gene_expression (production) of PGE2
1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Abstract Doc Link PMC2819253 Disease Relevance 0.15 Pain Relevance 0.32

General Comments

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