INT295239

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (Anxa1) cilium (Anxa1) protein complex (Anxa1)
cytoplasm (Anxa1) extracellular space (Anxa1) signal transduction (Anxa1)
Anatomy Link Frequency
microglia 1
Anxa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 80 100.00 Very High Very High Very High
Neuropathic pain 19 94.24 High High
Inflammation 35 90.88 High High
Inflammatory response 2 84.56 Quite High
dorsal root ganglion 7 70.44 Quite High
Sciatic nerve 44 70.12 Quite High
intrathecal 7 50.00 Quite Low
cytokine 6 45.36 Quite Low
Spinal cord 4 5.00 Very Low Very Low Very Low
allodynia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 86 100.00 Very High Very High Very High
Neuropathic Pain 25 94.24 High High
INFLAMMATION 41 90.88 High High
Injury 22 86.24 High High
Nervous System Injury 23 78.20 Quite High
Neurodegenerative Disease 5 76.44 Quite High
Ganglion Cysts 7 70.44 Quite High
Disease 3 13.64 Low Low
Apoptosis 20 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPC-induced ex vivo demyelination in the presence of ATX
Negative_regulation (demyelination) of LPC-induced associated with demyelination
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2989310 Disease Relevance 1.29 Pain Relevance 0.69
Lpcat1 is also highly expressed in the retina [44], indicating that luteolin-induced Lpact1 levels could lead to diminished LPC levels in retinal microglia.
Negative_regulation (diminished) of LPC in microglia
2) Confidence 0.02 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2819254 Disease Relevance 0.30 Pain Relevance 0.11

General Comments

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