INT29524

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Context Info
Confidence 0.45
First Reported 1985
Last Reported 1987
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (PDYN) extracellular region (PDYN) plasma membrane (PDYN)
Anatomy Link Frequency
enterocytes 4
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 11 100.00 Very High Very High Very High
antagonist 1 99.88 Very High Very High Very High
agonist 3 99.56 Very High Very High Very High
Immobilon 2 99.20 Very High Very High Very High
opiate 2 99.20 Very High Very High Very High
narcan 2 96.00 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction of Leu-enkephalin with isolated enterocytes from guinea pig: binding to specific receptors and stimulation of cAMP accumulation.
Positive_regulation (stimulation) of Leu-enkephalin Binding (binding) of in enterocytes associated with enkephalin
1) Confidence 0.45 Published 1985 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 2982375 Disease Relevance 0 Pain Relevance 0.33
Interaction of Leu-enkephalin with isolated enterocytes from guinea pig: binding to specific receptors and stimulation of cAMP accumulation.
Positive_regulation (stimulation) of Leu-enkephalin Binding (Interaction) of in enterocytes associated with enkephalin
2) Confidence 0.45 Published 1985 Journal Biochem. Biophys. Res. Commun. Section Title Doc Link 2982375 Disease Relevance 0 Pain Relevance 0.33
The effects of Na+ in 5 mM and 50 mM Tris-HCl were also investigated on the binding of other opiate receptor agonists and antagonists. [3H]D-Ala-D-Leu-enkephalin binding was increased and inhibited. [3H]etorphine binding increased and was unchanged, and both [3H]bremazocine and [3H]naloxone binding increased by 50 mM Na+ in 5 mM and 50 mM Tris-HCl, respectively.
Positive_regulation (increased) of D-Ala-D-Leu-enkephalin Binding (binding) of associated with antagonist, narcan, agonist, enkephalin, opiate and immobilon
3) Confidence 0.02 Published 1987 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 2835135 Disease Relevance 0 Pain Relevance 0.53

General Comments

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