INT295317

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

sulfur compound metabolic process (CHST3) Golgi apparatus (CHST3) carbohydrate metabolic process (CHST3)
Anatomy Link Frequency
leukocyte 2
CHST3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 32 75.36 Quite High
cytokine 25 74.32 Quite High
Inflammatory response 3 42.76 Quite Low
cva 5 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Catecholamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Injury 72 98.08 Very High Very High Very High
Death 5 96.76 Very High Very High Very High
Shock 7 94.04 High High
Injury 45 88.24 High High
INFLAMMATION 47 75.36 Quite High
Adhesions 39 68.88 Quite High
Sepsis 2 45.48 Quite Low
Systemic Inflammatory Response Syndrome 1 43.12 Quite Low
Pressure And Volume Under Development 5 5.00 Very Low Very Low Very Low
Coagulation Disorder 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the current results showing reduced surface expression of CD62L in HSD-treated patients, accompanied by corresponding increases in sL-selectin and better patient outcome, are in accordance with our previous findings in shock patients [14], and supports the theory that sL-selectin shedding represents an endogenous regulatory mechanism to limit leukocyte-mediated injury [79].


Negative_regulation (reduced) of Gene_expression (expression) of HSD in leukocyte associated with injury and shock
1) Confidence 0.13 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2819256 Disease Relevance 0.97 Pain Relevance 0.14

General Comments

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