INT295326

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Context Info
Confidence 0.65
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Sult1a1) response to stress (Sult1a1) cytoplasm (Sult1a1)
Anatomy Link Frequency
plasma 1
liver 1
Sult1a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 166 98.86 Very High Very High Very High
Inflammation 35 87.64 High High
Dopamine 1 49.28 Quite Low
Inflammatory response 3 30.24 Quite Low
cytokine 25 24.04 Low Low
cva 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Injury 72 97.56 Very High Very High Very High
Coagulation Disorder 5 90.80 High High
Toxicity 19 90.12 High High
INFLAMMATION 50 87.64 High High
Overdose 9 86.28 High High
Liver Failure 1 85.32 High High
Stress 2 63.12 Quite High
Injury 46 54.40 Quite High
Hepatotoxicity 5 52.16 Quite High
Thrombophilia 1 51.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on the measured plasma sTF, sTM and D-D levels, our results show that compared to control, NS-resuscitated TBI patients exhibit activation of coagulation with concurrent down-regulation of anticoagulant systems and fibrinolysis.
Gene_expression (levels) of sTM in plasma associated with brain injury
1) Confidence 0.65 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2819256 Disease Relevance 0.85 Pain Relevance 0.04
Acetaminophen is mainly metabolised, in the liver, via conjugation by sulphotransferase and UDP-glucuronosyltransferase and then excreted, but a small fraction of it is metabolised by CYP2E1 [7], [35].
Gene_expression (sulphotransferase) of sulphotransferase in liver associated with paracetamol
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000821 Disease Relevance 0.44 Pain Relevance 1.02

General Comments

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