INT295337

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ptpn11) mitochondrion (Ptpn11) extracellular space (Egf)
plasma membrane (Egf) protein complex (Ptpn11) lipid metabolic process (Ptpn11)
Anatomy Link Frequency
nucleus 1
Egf (Rattus norvegicus)
Ptpn11 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 4 99.12 Very High Very High Very High
dorsal root ganglion 14 5.00 Very Low Very Low Very Low
Dynorphin 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 76.24 Quite High
Ganglion Cysts 14 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Diuresis 1 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
–opioid receptor (OR [KOR]) as a model, we demonstrate that EGF activates nuclear SHP-2 (Src homology region 2–containing tyrosine phosphatase), which dephosphorylates Grb7 in the nucleus.
EGF Positive_regulation (activates) of SHP-2 in nucleus associated with opioid receptor
1) Confidence 0.15 Published 2010 Journal The Journal of Cell Biology Section Abstract Doc Link PMC2819679 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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