INT295383

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (Xpo1) nucleoplasm (Xpo1) nucleolus (Xpo1)
RNA binding (Xpo1) nucleus (Xpo1) cytoplasm (Xpo1)
Xpo1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 28 82.56 Quite High
opioid receptor 8 5.00 Very Low Very Low Very Low
Dynorphin 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 28 82.56 Quite High
Pain 4 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Diuresis 2 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HuR utilizes three different complexes for nuclear export, including exportin-1 (also known as CRM1) and transportin 1 and 2 (Brennan et al., 2000; Rebane et al., 2004).
Localization (export) of exportin-1
1) Confidence 0.16 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2819679 Disease Relevance 0.14 Pain Relevance 0.07
The interaction between HuR–CRM1 was not affected, confirming the specificity of SHP-2 in dephosphorylating Grb7 and its subsequent complex formation with the HuR–CRM1 export complex.


Localization (export) of CRM1
2) Confidence 0.16 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2819679 Disease Relevance 0 Pain Relevance 0

General Comments

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