INT295426

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (KIT, PDGFRB) plasma membrane (KIT, PDGFRB) nucleus (KIT, PDGFRB)
cytoplasm (KIT, PDGFRB) extracellular space (KIT) cytoplasmic membrane-bounded vesicle (PDGFRB)
KIT (Homo sapiens)
PDGFRB (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gastrointestinal Stromal Tumor 104 96.96 Very High Very High Very High
Disease 62 73.60 Quite High
Metastasis 4 41.44 Quite Low
Carcinoma 1 29.88 Quite Low
Sarcoma 5 7.76 Low Low
Cancer 46 5.00 Very Low Very Low Very Low
Disease Progression 12 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low
Watson Syndrome 4 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nilotinib is a second generation small molecule TKI with good activity against receptors of KIT and PDGFR.
KIT Binding (receptors) of PDGFR
1) Confidence 0.24 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2819895 Disease Relevance 0.40 Pain Relevance 0

General Comments

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