INT295451

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.26
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (Gpt) cellular_component (Gpt) biological_process (Gpt)
cytoplasm (Gpt)
Gpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 2 100.00 Very High Very High Very High
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 45 99.98 Very High Very High Very High
Cancer 30 94.72 High High
Pressure And Volume Under Development 1 90.68 High High
Disease 2 28.28 Quite Low
Sprains And Strains 45 5.00 Very Low Very Low Very Low
Body Weight 17 5.00 Very Low Very Low Very Low
Toxicity 12 5.00 Very Low Very Low Very Low
Hepatotoxicity 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This gpt delta rat carries approximately five copies of ?
Negative_regulation (This) of Gene_expression (rat) of gpt
1) Confidence 0.38 Published 2010 Journal Toxicological Sciences Section Body Doc Link PMC2819973 Disease Relevance 0.35 Pain Relevance 0
In 2003, we established gpt delta rats in a Sprague-Dawley (SD) background by introducing ?
Negative_regulation (established) of Gene_expression (rats) of gpt
2) Confidence 0.38 Published 2010 Journal Toxicological Sciences Section Body Doc Link PMC2819973 Disease Relevance 0.36 Pain Relevance 0
A feature of this transgenic mouse is that two mutant selections can be performed instead of just one, to identify a wider spectrum of in vivo mutations: gpt selection to identify point mutations such as base substitutions and frameshift mutations and Spi?
Negative_regulation (is) of Gene_expression (selection) of gpt associated with targeted disruption
3) Confidence 0.33 Published 2010 Journal Toxicological Sciences Section Body Doc Link PMC2819973 Disease Relevance 0.47 Pain Relevance 0
Preliminary studies in our lab show no significant changes in super oxide dismutase activity (SOD), protein, alkaline phosphatase, SGOT (serum glutamate oxalo transaminase), SGPT (serum glutamate pyruvate transaminase), creatinine, lipid peroxidase, serum urea in Naga bhasma-treated and untreated rat groups.
Negative_regulation (creatinine) of Gene_expression (activity) of serum glutamate pyruvate transaminase associated with glutamate
4) Confidence 0.05 Published 2010 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC2883223 Disease Relevance 0.09 Pain Relevance 0.10

General Comments

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