INT295476

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PIK3CA, TNF) cytosol (PIK3CA) extracellular space (TNF)
extracellular region (TNF) plasma membrane (TNF) intracellular (TNF)
PIK3CA (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C inhibitor 1 67.60 Quite High
Inflammation 15 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 68 51.48 Quite High
INFLAMMATION 15 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of PI3Kinase in the secretion and genetic expression of TNFalpha was determined by the use of two different inhibitors to this pathway (wortmannin, Sigma-Aldrich and LY294002, Cayman Chemical, France).
PI3Kinase Regulation (role) of Gene_expression (expression) of TNFalpha
1) Confidence 0.00 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2819999 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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