INT295529

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, Gh) extracellular region (Ghrl, Gh) mitochondrion (Gh)
cytoplasm (Ghrl) cytosol (Gh) signal transduction (Gh)
Anatomy Link Frequency
pituitary 2
Ghrl (Mus musculus)
Gh (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 3 63.84 Quite High
Somatostatin 11 61.84 Quite High
Action potential 22 5.00 Very Low Very Low Very Low
antagonist 13 5.00 Very Low Very Low Very Low
GABAergic 9 5.00 Very Low Very Low Very Low
Calcium channel 9 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to its direct effects on the pituitary, ghrelin clearly targets GH release indirectly at the level of the arcuate nucleus since: 1) anatomical disconnections between the hypothalamus and the pituitary gland blunt GH secretion induced by GHS in vivo [13], [14]; 2) the GHSR is expressed in GHRH neurons, which trigger GH release by the pituitary gland [8]–[11]; 3) in vivo GHS treatments enhance GHRH secretion in sheep [1], [15] and induce c-fos expression in GHRH neurons in rodents [16].
ghrelin Regulation (targets) of Localization (release) of GH in pituitary
1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2820089 Disease Relevance 0 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox