INT29554

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Context Info
Confidence 0.40
First Reported 1986
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.12
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Ebp) endoplasmic reticulum (Ebp)
Anatomy Link Frequency
pituitary 1
Ebp (Rattus norvegicus)
LH (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 6 99.76 Very High Very High Very High
Morphine 3 98.16 Very High Very High Very High
analgesia 2 96.80 Very High Very High Very High
opiate 3 94.56 High High
antagonist 2 94.00 High High
Endogenous opioid 4 91.28 High High
antinociception 1 82.24 Quite High
Antinociceptive 2 78.84 Quite High
Spinal cord 1 75.60 Quite High
tail-flick 1 70.88 Quite High
Disease Link Frequency Relevance Heat
Hypothermia 1 68.40 Quite High
Attention Deficit Hyperactivity Disorder 1 52.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Naloxone (0.1-15.0 mg/kg) was injected before (1200 h) and during (1400 and 1530 h) the LH surge induced by EBP treatment and during the LH surge after EB treatment (1600 h).
EBP Positive_regulation (induced) of LH associated with narcan
1) Confidence 0.40 Published 1986 Journal Endocrinology Section Abstract Doc Link 3510853 Disease Relevance 0 Pain Relevance 0.39
This decline in the LH secretory response to naloxone during the EBP-induced LH surge was not due to changes in the response of pituitary to LHRH.
EBP Positive_regulation (induced) of LH in pituitary associated with narcan
2) Confidence 0.40 Published 1986 Journal Endocrinology Section Abstract Doc Link 3510853 Disease Relevance 0 Pain Relevance 0.37
In OVX and EB rats, MS caused a dose-dependent decrease in serum LH, but even 20 mg/kg MS did not alter serum LH during the EBP-induced LH surge.
EBP Positive_regulation (induced) of LH
3) Confidence 0.31 Published 1988 Journal Endocrinology Section Abstract Doc Link 2836173 Disease Relevance 0.12 Pain Relevance 0.64

General Comments

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