INT295548

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, Ghrh) extracellular region (Ghrl, Ghrh) cytoplasm (Ghrl)
Anatomy Link Frequency
neurons 4
Ghrl (Mus musculus)
Ghrh (Mus musculus)
Pain Link Frequency Relevance Heat
Action potential 44 96.60 Very High Very High Very High
Calcium channel 18 88.56 High High
TRP channel 2 72.48 Quite High
Somatostatin 22 41.20 Quite Low
antagonist 26 29.76 Quite Low
agonist 16 25.84 Quite Low
GABAergic 18 5.00 Very Low Very Low Very Low
gABA 12 5.00 Very Low Very Low Very Low
Neuropeptide 6 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Perforated patch clamp results showed that ghrelin depolarized GHRH neurons in a tonic manner, and did not significantly modify the kinetics of the spontaneous action potentials.
ghrelin Neg (not) Regulation (depolarized) of Regulation (neurons) of GHRH in neurons associated with action potential
1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2820089 Disease Relevance 0 Pain Relevance 0.31
Ghrelin increased the spontaneous firing rate, but did not modify either the firing pattern or the synchronisation amongst GHRH neurons.
Ghrelin Neg (not) Regulation (modify) of Regulation (synchronisation) of GHRH in neurons
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2820089 Disease Relevance 0 Pain Relevance 0.13

General Comments

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