INT295617

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (SPTLC1) endoplasmic reticulum (SPTLC1) biosynthetic process (SPTLC1)
cytoskeleton (UBXN11) transferase activity, transferring acyl groups (SPTLC1) cytoplasm (UBXN11)
UBXN11 (Homo sapiens)
SPTLC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 65 92.36 High High
Proteinuria 18 91.04 High High
Renal Disease 61 84.60 Quite High
Hyperinsulinism 1 81.52 Quite High
Disease Susceptibility 6 72.64 Quite High
Obesity 2 37.80 Quite Low
Congenital Anomalies 1 30.08 Quite Low
Chronic Renal Failure 13 26.80 Quite Low
Diabetic Retinopathy 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ACACB encodes acetyl-coenzyme A (CoA) carboxylase beta, which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, and controls fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine palmitoyl transferase I (CPT1A; MIM 600528), the rate-limiting step in fatty acid uptake and oxidation by mitochondria in non-lipogenic tissues.
CoA Negative_regulation (inhibit) of carnitine palmitoyl transferase I
1) Confidence 0.03 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2820513 Disease Relevance 0.57 Pain Relevance 0

General Comments

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