INT295681

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (CDC42EP1) plasma membrane (CDC42EP1) cytoplasm (CDC42EP1)
Anatomy Link Frequency
fibroblast 1
CDC42EP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 80 50.00 Quite Low
metalloproteinase 204 5.00 Very Low Very Low Very Low
cytokine 152 5.00 Very Low Very Low Very Low
COX-2 inhibitor 46 5.00 Very Low Very Low Very Low
chemokine 40 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Virus 476 99.84 Very High Very High Very High
Infection 208 99.64 Very High Very High Very High
Adhesions 84 91.84 High High
Sarcoma 158 50.00 Quite Low
INFLAMMATION 88 50.00 Quite Low
Cancer 40 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, we asked the question whether secreted factors participate in the activation of RhoA- or Rac-GTPases.
Spec (whether) Positive_regulation (activation) of GTPases
1) Confidence 0.01 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 1.06 Pain Relevance 0
Our earlier studies have demonstrated the activation of these GTPases by KSHV infection and stimulation by interaction of the KSHV envelope glycoprotein gB with adherent endothelial or fibroblast cell integrins [25],[35],[52].
Positive_regulation (activation) of GTPases in fibroblast associated with herpes simplex virus and infection
2) Confidence 0.01 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 1.58 Pain Relevance 0

General Comments

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