INT295683

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Context Info
Confidence 0.49
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.72
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RAC2) signal transduction (RAC2) nuclear envelope (RAC2)
plasma membrane (RAC2) intracellular (RAC2) GTPase activity (RAC2)
Anatomy Link Frequency
endothelial cells 1
RAC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 102 86.60 High High
cytokine 76 84.16 Quite High
Inflammation 40 81.00 Quite High
COX-2 inhibitor 23 57.92 Quite High
chemokine 20 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 42 98.98 Very High Very High Very High
Infection 104 98.28 Very High Very High Very High
Herpes Simplex Virus 238 98.08 Very High Very High Very High
Sarcoma 79 83.52 Quite High
INFLAMMATION 44 81.00 Quite High
Apoptosis 8 68.24 Quite High
Vascular Neoplasms 1 39.36 Quite Low
Disease 5 32.40 Quite Low
Cancer 20 25.00 Low Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PGE2, secreted early during KSHV infection, profoundly increased the adhesion of uninfected endothelial cells to fibronectin by activating the small G protein Rac1.
Positive_regulation (activating) of small G protein in endothelial cells associated with herpes simplex virus, adhesions and infection
1) Confidence 0.49 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2820536 Disease Relevance 1.72 Pain Relevance 0.30

General Comments

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