INT295688

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 204 100.00 Very High Very High Very High
Inflammation 80 50.00 Quite Low
cytokine 152 42.88 Quite Low
COX-2 inhibitor 46 5.00 Very Low Very Low Very Low
chemokine 40 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Virus 476 99.98 Very High Very High Very High
Infection 208 98.40 Very High Very High Very High
Sarcoma 158 50.00 Quite Low
INFLAMMATION 88 50.00 Quite Low
Adhesions 84 5.00 Very Low Very Low Very Low
Cancer 40 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COX inhibitor treatment of TIVE-LTC inhibited total as well as active-MMP-9 secretion (Figure 9D), indicating the importance of COX-2 in regulating MMP-9.
Positive_regulation (importance) of Regulation (regulating) of MMP-9 associated with metalloproteinase
1) Confidence 0.14 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.33 Pain Relevance 0.78
NS-398 treatment prior to infection inhibited total as well as active-MMP-9 secretion implicating the role of KSHV induced COX-2 in regulating MMP-9 (Figure 9A).
Positive_regulation (induced) of Regulation (regulating) of MMP-9 associated with herpes simplex virus, metalloproteinase and infection
2) Confidence 0.12 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.34 Pain Relevance 0.73

General Comments

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