INT295702

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Racgap1) transport (Racgap1) intracellular (Racgap1)
embryo development (Racgap1) cytoplasm (Racgap1) signal transducer activity (PTGER2)
Anatomy Link Frequency
endothelial cells 1
PTGER2 (Homo sapiens)
Racgap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 50.00 Quite Low
metalloproteinase 102 5.00 Very Low Very Low Very Low
cytokine 76 5.00 Very Low Very Low Very Low
COX-2 inhibitor 23 5.00 Very Low Very Low Very Low
chemokine 20 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 104 77.40 Quite High
Herpes Simplex Virus 238 77.00 Quite High
Adhesions 42 65.24 Quite High
Sarcoma 79 50.00 Quite Low
INFLAMMATION 44 50.00 Quite Low
Cancer 20 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Induction of Rac1-GTPase was 4.8- fold when compared to Rac1-GTPase activity in the presence of uninfected cell culture supernatant suggesting that PGE2 is enough to induce Rac1-GTPase in the adhering endothelial cells.
PGE2 Positive_regulation (induce) of GTPase in endothelial cells
1) Confidence 0.05 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.22 Pain Relevance 0

General Comments

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