INT295711

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MMP9, VEGFA) extracellular region (MMP9, VEGFA) proteinaceous extracellular matrix (MMP9, VEGFA)
extracellular matrix organization (MMP9) protein complex (MMP9) cytoplasm (VEGFA)
Anatomy Link Frequency
endothelial cells 2
MMP9 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 102 100.00 Very High Very High Very High
Bioavailability 1 99.76 Very High Very High Very High
cytokine 76 79.20 Quite High
COX-2 inhibitor 23 78.40 Quite High
chemokine 20 76.24 Quite High
Inflammation 40 50.00 Quite Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 104 74.40 Quite High
Herpes Simplex Virus 238 55.08 Quite High
Sarcoma 79 52.84 Quite High
INFLAMMATION 44 50.00 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 48.76 Quite Low
Hepatitis B Virus Infection 1 48.20 Quite Low
Hepatitis 1 47.68 Quite Low
Epstein-barr Virus 2 46.64 Quite Low
Cancer 20 43.72 Quite Low
Metastasis 3 43.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MMP-9 has the potential to increase VEGF release, its bioavailability to bind to VEGF receptors on endothelial cells, and thus leading to an angiogenic loop that eventually will result in cell migration, cell proliferation and angiogenesis [69].
MMP-9 Positive_regulation (increase) of Localization (release) of VEGF in endothelial cells associated with metalloproteinase and bioavailability
1) Confidence 0.06 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.29 Pain Relevance 0.74

General Comments

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