INT295720

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) plasma membrane (PTGER2) extracellular matrix organization (MMP9)
PTGER2 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 102 100.00 Very High Very High Very High
Bioavailability 1 87.36 High High
COX-2 inhibitor 23 83.72 Quite High
cytokine 76 67.04 Quite High
chemokine 20 64.08 Quite High
Inflammation 40 50.00 Quite Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 104 79.72 Quite High
Herpes Simplex Virus 238 60.40 Quite High
Sarcoma 79 58.16 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 54.08 Quite High
Hepatitis B Virus Infection 1 53.52 Quite High
Hepatitis 1 53.00 Quite High
Epstein-barr Virus 2 51.96 Quite High
INFLAMMATION 44 50.00 Quite Low
Cancer 20 49.04 Quite Low
Metastasis 3 48.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COX-2/PGE2 probably regulates MMP-9 at the transcriptional level by activating transcription factors like AP-1, Ets2, NF-?
PGE2 Regulation (regulates) of MMP-9 associated with metalloproteinase
1) Confidence 0.01 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.53 Pain Relevance 0.70

General Comments

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