INT295849

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Context Info
Confidence 0.60
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Srsf1) mRNA processing (Srsf1) RNA binding (Srsf1)
nucleus (Srsf1) cytoplasm (Srsf1)
Srsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Myeloid Leukemia 3 80.48 Quite High
Leukemia 3 76.60 Quite High
Apoptosis 3 62.96 Quite High
Cancer 21 58.16 Quite High
Lung Cancer 3 27.08 Quite Low
Targeted Disruption 3 25.72 Quite Low
Sarcoma 3 24.00 Low Low
Skin Cancer 6 15.84 Low Low
Breast Cancer 3 13.88 Low Low
Colon Cancer 6 13.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It thus appears likely that SRPK1-mediated phosphorylation of ASF/SF2 could support an activation of the PSS and increased production of pro-angiogenic isoforms.
Positive_regulation (mediated) of Phosphorylation (phosphorylation) of ASF/SF2
1) Confidence 0.60 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0.13 Pain Relevance 0
It thus appears likely that SRPK1-mediated phosphorylation of ASF/SF2 could support an activation of the PSS and increased production of pro-angiogenic isoforms.
Positive_regulation (activation) of Phosphorylation (phosphorylation) of ASF/SF2
2) Confidence 0.44 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0.13 Pain Relevance 0
These results indicate that an overactivity of SRPK1 can cause phosphorylation of ASF/SF2.
Positive_regulation (cause) of Phosphorylation (phosphorylation) of ASF/SF2
3) Confidence 0.40 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0.38 Pain Relevance 0

General Comments

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