INT295856

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkca, Srsf1) nucleus (Prkca, Srsf1) nucleoplasm (Srsf1)
mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca)
Prkca (Mus musculus)
Srsf1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinal Neovascularization 3 7.20 Low Low
Cancer 7 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 5 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 5 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Skin Cancer 2 5.00 Very Low Very Low Very Low
Glaucoma 2 5.00 Very Low Very Low Very Low
Pathologic Neovascularization 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine whether binding of ASF/SF2 was PKC-dependent and whether this was SRPK1-dependent, HEK293 cells were treated with the PKC activator PMA in the presence or absence of the SRPK inhibitor SRPIN340, and then the protein run on an MS2-MBP column with the VEGF exon 8 construct.
PKC-dependent Spec (whether) Binding (binding) of ASF/SF2
1) Confidence 0.10 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2820781 Disease Relevance 0 Pain Relevance 0

General Comments

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