INT296002

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Context Info
Confidence 0.56
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.48
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egln3) cytoplasm (Egln3)
Egln3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
isoflurane 12 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperoxia 330 98.36 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 162 97.96 Very High Very High Very High
Hypoxia 132 96.16 Very High Very High Very High
Retinal Neovascularization 6 92.84 High High
Disease Progression 12 82.64 Quite High
Cancer 6 19.12 Low Low
Apoptosis 6 17.76 Low Low
Sprains And Strains 222 5.00 Very Low Very Low Very Low
Retinopathy 54 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 48 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A decrease in Egln3, as observed in our study, might be expected to result in the stabilization of HIF-1?
Negative_regulation (decrease) of Egln3
1) Confidence 0.56 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.41 Pain Relevance 0
At post-natal day 3, Egln3 was found to be decreased 5.1-fold in SD rats in response to cyclic hyperoxic exposure.
Negative_regulation (decreased) of Egln3
2) Confidence 0.42 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.53 Pain Relevance 0
Egln3 was decreased to a lesser extent (2.1-fold) in cyclic hyperoxia-exposed F344 rats compared to room air-exposed rats.
Negative_regulation (decreased) of Egln3 associated with hyperoxia
3) Confidence 0.42 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.54 Pain Relevance 0

General Comments

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