INT296004

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Context Info
Confidence 0.67
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egln3) cytoplasm (Egln3)
Egln3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
isoflurane 8 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 88 98.20 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 108 96.24 Very High Very High Very High
Disease Progression 8 92.48 High High
Hyperoxia 220 84.56 Quite High
Retinal Neovascularization 4 70.88 Quite High
Sprains And Strains 148 5.00 Very Low Very Low Very Low
Retinopathy 36 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 32 5.00 Very Low Very Low Very Low
Congenital Anomalies 12 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At the later time points of P20 (rat) and P18 (mouse), Egln3 expression increased by 3.0- and 5.3-fold, respectively.
Positive_regulation (increased) of Gene_expression (expression) of Egln3
1) Confidence 0.67 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.72 Pain Relevance 0
These increases in Egln3 expression may be a result of the response to relative hypoxia, particularly at the later time point of OIR, rather than in response to hyperoxic exposure.
Positive_regulation (increases) of Gene_expression (expression) of Egln3 associated with hypoxia and ocular toxicity (including many sub-types)
2) Confidence 0.67 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2821581 Disease Relevance 1.64 Pain Relevance 0

General Comments

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