INT296034

Context Info Confidence 0.10 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.63 Pain Relevance 0.08

cell morphogenesis (IL7R) intracellular (FOXP3) embryo development (FOXP3) protein complex (FOXP3) cytoplasm (FOXP3) signal transduction (IL7R)

FOXP3 (Homo sapiens) IL7R (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 32 83.64 cytokine 36 71.08 tolerance 13 47.88 Crohn's disease 4 5.00 adenocard 3 5.00 chemokine 3 5.00 withdrawal 1 5.00 Nerve growth factor 1 5.00 Inflammatory response 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Infection 1 85.56 Hypersensitivity 2 84.64 Inflammatory Bowel Disease 30 84.20 Autoimmune Disease 12 81.88 Syndrome 1 78.72 Enteropathy 1 77.80 Repression 2 58.20 INFLAMMATION 30 50.00 Congenital Anomalies 1 49.20 Communicable Diseases 2 45.96

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

FoxP3 can also interact with the promoter of IL-127 receptor (IL-127R) and might contribute to reduce expression of CD127 in Tregs.

FoxP3 Negative_regulation (reduce) of Gene_expression (expression) of CD127

1) Confidence 0.10 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.63 Pain Relevance 0.08

General Comments

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