INT296068

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (CTLA4) plasma membrane (CTLA4)
CTLA4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 73.88 Quite High
Inflammation 32 66.76 Quite High
adenocard 3 63.80 Quite High
Nerve growth factor 1 28.48 Quite Low
tolerance 13 19.60 Low Low
cytokine 36 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 12 75.92 Quite High
Pain 1 73.88 Quite High
INFLAMMATION 30 66.76 Quite High
Repression 2 46.04 Quite Low
Disease 22 43.08 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 42.76 Quite Low
Apoptosis 3 39.24 Quite Low
Cancer 33 38.16 Quite Low
Necrosis 2 37.68 Quite Low
Inflammatory Bowel Disease 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Constitutive expression of CTLA-4 among CD4+ cells was restricted primarily to Tregs, suggesting that CTLA-4 expression by these cells is involved in their immune-suppressive function.
Regulation (involved) of Gene_expression (expression) of CTLA-4
1) Confidence 0.16 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.22 Pain Relevance 0.20

General Comments

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