INT296150

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Chek1) nucleus (Chek1) cell cycle (Chek1)
kinase activity (Chek1) cytoplasm (Chek1)
Chek1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 7 55.92 Quite High
Disease 5 35.36 Quite Low
Microcephaly 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Chromosome Breakage 5 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Chromosome Aberrations 2 5.00 Very Low Very Low Very Low
Lifespan 2 5.00 Very Low Very Low Very Low
Metastasis 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More specifically, there was no significant reduction in the expression levels of Chk1, Brca1, Topbp1, Rad51, Ddb2, p73, Apaf1, or caspases which were all described to show reduced expression following MCPH1 knockdowns [34] (Tables S3, S4, S5).
Neg (no) Negative_regulation (reduction) of Gene_expression (expression) of Chk1
1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0.11 Pain Relevance 0

General Comments

This test has worked.

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