INT296151

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Context Info
Confidence 0.78
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 13
Disease Relevance 1.33
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Mcph1) intracellular (Mcph1) molecular_function (Mcph1)
cellular_component (Mcph1) biological_process (Mcph1) cytoplasm (Mcph1)
Anatomy Link Frequency
liver 1
brain 1
spleen 1
Mcph1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 39 97.20 Very High Very High Very High
isoflurane 13 96.88 Very High Very High Very High
cerebral cortex 26 5.00 Very Low Very Low Very Low
anesthesia 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 52 99.52 Very High Very High Very High
Genomic Instability 13 98.76 Very High Very High Very High
Ovarian Cancer 13 98.28 Very High Very High Very High
Metastasis 13 97.80 Very High Very High Very High
Dislocations 13 94.96 High High
Cancer 13 93.52 High High
Syndrome 78 65.76 Quite High
Body Weight 13 34.80 Quite Low
Microcephaly 78 24.40 Low Low
Neurodegenerative Disease 91 21.48 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results revealed that in comparison to the low-abundant endogenous control gene Hprt, Mcph1 is expressed at very low levels in all analyzed tissues.
Spec (analyzed) Gene_expression (expressed) of Mcph1
1) Confidence 0.78 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
Generation of the Mcph1 Deficient Mice
Gene_expression (Generation) of Mcph1
2) Confidence 0.78 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
Control and Mcph1gt/gt mice at 15 weeks of age (n?
Gene_expression (Control) of Mcph1gt
3) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0.09 Pain Relevance 0.03
This may be explained by low expression rates of Mcph1.
Gene_expression (expression) of Mcph1
4) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
5), and homozygous Mcph1gt/gt (n?
Gene_expression (/) of Mcph1gt
5) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0.14
We compared the expression in liver, brain, and spleen of three Mcph1gt/gt animals to three controls by relative quantification.
Gene_expression (expression) of Mcph1gt in spleen
6) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
Thus, our problems detecting the Mcph1 protein can be explained by these very low expression levels.
Gene_expression (detecting) of Mcph1 protein
7) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
Control and Mcph1gt/gt mice at 15 weeks of age (n?
Gene_expression (/) of Mcph1gt
8) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0.09 Pain Relevance 0.03
MCPH1 expression was inversely correlated with genomic instability and metastasis.
Gene_expression (expression) of MCPH1 associated with genomic instability and metastasis
9) Confidence 0.60 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0.63 Pain Relevance 0
These findings correlate with data obtained by the cloning and expression of chicken Mcph1 [16].
Gene_expression (expression) of Mcph1
10) Confidence 0.60 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0.52 Pain Relevance 0
Ct-method using Mcph1-specific primers F1: 5?
Gene_expression (using) of Mcph1
11) Confidence 0.59 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
We compared the expression in liver, brain, and spleen of three Mcph1gt/gt animals to three controls by relative quantification.
Gene_expression (expression) of Mcph1gt in brain
12) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0
We compared the expression in liver, brain, and spleen of three Mcph1gt/gt animals to three controls by relative quantification.
Gene_expression (expression) of Mcph1gt in liver
13) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821930 Disease Relevance 0 Pain Relevance 0

General Comments

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