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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.06
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2b) plasma membrane (Grin2b) embryo development (Grin2b)
Anatomy Link Frequency
spinal cord 2
Grin2b (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 61 100.00 Very High Very High Very High
Spinal cord 29 100.00 Very High Very High Very High
Eae 16 98.32 Very High Very High Very High
Hippocampus 13 94.80 High High
Pain 20 76.92 Quite High
Dorsal horn 21 65.84 Quite High
Thermal hyperalgesia 8 62.88 Quite High
nociceptor 11 61.72 Quite High
antagonist 5 52.64 Quite High
allodynia 9 50.48 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 88 99.44 Very High Very High Very High
Inflammatory Pain 9 98.32 Very High Very High Very High
Repression 1 80.52 Quite High
Pain 25 76.92 Quite High
Hyperalgesia 10 62.88 Quite High
Neuropathic Pain 32 50.48 Quite High
Depression 31 50.00 Quite Low
Anxiety Disorder 24 50.00 Quite Low
INFLAMMATION 10 50.00 Quite Low
Nociception 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found no change in the phosphorylation of NMDA receptor subunits NR1, NR2A or NR2B in TgDREAM mice (Figure 5B).
Neg (no) Regulation (change) of Phosphorylation (phosphorylation) of NR2B associated with nmda receptor
1) Confidence 0.44 Published 2010 Journal Mol Brain Section Body Doc Link PMC2822766 Disease Relevance 0.14 Pain Relevance 0.59
NR2B phosphorylation in spinal cord of ephrin-B2 CKO mutants is lost in some inflammatory pain models
Regulation (spinal cord) of Phosphorylation (phosphorylation) of NR2B in spinal cord associated with targeted disruption, eae and spinal cord
2) Confidence 0.27 Published 2010 Journal Mol Pain Section Body Doc Link PMC2992507 Disease Relevance 0.92 Pain Relevance 0.81

General Comments

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