INT296283

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Kcnip3, Cysltr1) transport (Kcnip3) Golgi apparatus (Kcnip3)
endoplasmic reticulum (Kcnip3) intracellular (Kcnip3) DNA binding (Kcnip3)
Kcnip3 (Mus musculus)
Cysltr1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 53 100.00 Very High Very High Very High
depression 31 100.00 Very High Very High Very High
Hippocampus 12 91.92 High High
Glutamate receptor 2 88.24 High High
long-term potentiation 20 84.92 Quite High
Lasting pain 2 56.40 Quite High
antagonist 5 50.00 Quite Low
Dynorphin 2 12.96 Low Low
tail-flick 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 31 100.00 Very High Very High Very High
Targeted Disruption 21 69.72 Quite High
Pain 3 56.40 Quite High
Anxiety Disorder 24 50.00 Quite Low
Shock 9 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Brain Disease 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we propose that DREAM binds with PSD95 and thus affects NMDA receptor function and the induction of LTD.
DREAM Regulation (affects) of Positive_regulation (induction) of LTD associated with depression and nmda receptor
1) Confidence 0.01 Published 2010 Journal Mol Brain Section Body Doc Link PMC2822766 Disease Relevance 0.85 Pain Relevance 0.94

General Comments

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