INT29636

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Context Info
Confidence 0.73
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.10
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PAM) lyase activity (PAM) extracellular region (PAM)
Anatomy Link Frequency
DA neurons 1
tubules 1
PAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 2 100.00 Very High Very High Very High
Somatostatin 2 100.00 Very High Very High Very High
Dopamine 108 99.82 Very High Very High Very High
Eae 37 98.16 Very High Very High Very High
Inflammation 13 40.24 Quite Low
cryotherapy 9 34.00 Quite Low
Neuropeptide 1 25.00 Low Low
cytokine 24 12.64 Low Low
tolerance 10 5.00 Very Low Very Low Very Low
alcohol 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 27 99.80 Very High Very High Very High
Cancer 99 97.12 Very High Very High Very High
Melanoma 23 96.00 Very High Very High Very High
Pigment Disorder 1 94.56 High High
Metastasis 6 89.52 High High
Syndrome 1 86.48 High High
Vipoma 1 86.12 High High
Freckles 14 79.36 Quite High
Ganglioneuroma 1 79.36 Quite High
Ganglioneuroblastoma 1 77.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The pancreatic and jejunal tumors showed all structural and secretory patterns of epithelial endocrine tumors, including expression of cytokeratin, neuroendocrine markers like neuron-specific enolase, chromogranins and synaptophysin, peptides like VIP, PHM, GRH, PP, insulin, neurotensin, glucagon, somatostatin and enkephalin, secretory granules, small clear vesicles, peculiar osmiophilic bodies, and occasional formation of tubules or microacini with specialized luminal surfaces.
Localization (secretory) of PHM in tubules associated with cancer, somatostatin and enkephalin
1) Confidence 0.73 Published 1988 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 2839087 Disease Relevance 0.93 Pain Relevance 0.26
In order to select these subjects, 300 adolescents and 300 young adults are asked to wear a PAM accelerometer during their daily activities for two weeks.
Localization (accelerometer) of PAM
2) Confidence 0.64 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1351198 Disease Relevance 0 Pain Relevance 0
PAM can be differentiated histologically into two types:[24]
Localization (differentiated) of PAM
3) Confidence 0.14 Published 2009 Journal Oman Journal of Ophthalmology Section Body Doc Link PMC3018103 Disease Relevance 0.87 Pain Relevance 0
Thus, the stimulation of locomotor activity by activation of either TH-GAL4 or c346 neurons was specific, and the subset of DA neurons labeled by the Ddc(HL5) transgene (PAL, PAM, PPL2, PPM1/2, Sb) could not be the sole source of a DA-dependent locomotor activation signal.
Localization (labeled) of PAM in DA neurons associated with dopamine and eae
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2848596 Disease Relevance 0 Pain Relevance 0.62
To determine whether cellular activation may regulate TLR mRNA levels, cells were stimulated with LPS, Pam3Cys and M.tb DNA, for 1 h and 24 h, respectively.
Localization (stimulated) of Pam3Cys associated with mycobacterial infection
5) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC2817655 Disease Relevance 0.30 Pain Relevance 0

General Comments

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