INT296382

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.49
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC11A2) nucleus (SLC11A2) vacuole (SLC11A2)
transmembrane transport (SLC11A2) lysosome (SLC11A2) cytoplasm (SLC11A2)
SLC11A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 23 88.80 High High
cINOD 10 5.00 Very Low Very Low Very Low
aspirin 8 5.00 Very Low Very Low Very Low
nud 6 5.00 Very Low Very Low Very Low
Restless leg syndrome 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
peptic ulcer disease 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Iron-deficiency Anemia 190 99.96 Very High Very High Very High
INFLAMMATION 23 88.80 High High
Lead Poisoning 2 79.12 Quite High
Thalassemia 11 78.72 Quite High
Chronic Disease 18 77.84 Quite High
Hemoglobinopathy 2 77.12 Quite High
Anaemia 92 64.40 Quite High
Disease 25 63.00 Quite High
Hemorrhage 40 61.04 Quite High
Inflammatory Bowel Disease 48 59.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations in ALAS2, SLC25A28 (MFRN2) and SLC11A2 (DMT1) were excluded in previous analyses.
Positive_regulation (Mutations) of SLC11A2
1) Confidence 0.31 Published 2010 Journal Biochemical Journal Section Body Doc Link PMC2958558 Disease Relevance 0.08 Pain Relevance 0
Inorganic iron may be absorbed via the divalent metal transporter-1 (DMT-1), a protein that transports a number of divalent metals, including ferrous iron (Fe2+).
Positive_regulation (divalent) of DMT-1
2) Confidence 0.05 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 0.77 Pain Relevance 0
In IDA, DMT-1 is upregulated, which increases zinc transport across the intestinal membrane to replace the missing iron in the formation of the protoporphyrin ring [38].
Positive_regulation (upregulated) of DMT-1 associated with iron-deficiency anemia
3) Confidence 0.05 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 0.64 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox