INT296384

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC40A1) transmembrane transport (SLC40A1) cytoplasm (SLC40A1)
Anatomy Link Frequency
liver 1
SLC40A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 54.48 Quite High
fibrosis 8 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
nud 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Parenteral administration 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 90.80 High High
Pressure Volume 2 Under Development 13 89.52 High High
Hemorrhage 20 84.48 Quite High
Iron-deficiency Anemia 96 83.20 Quite High
Anaemia 51 70.48 Quite High
Hypoxia 1 69.84 Quite High
Iron Overload 48 66.32 Quite High
INFLAMMATION 16 54.48 Quite High
Thalassemia 41 36.96 Quite Low
Sickle Cell Anemia 86 35.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of ferroportin on the cell membrane is regulated by hepcidin, a 25-amino acid peptide synthesized by the liver that is the principal hormone involved in regulating iron absorption [5].
Regulation (regulated) of ferroportin in liver
1) Confidence 0.01 Published 2010 Journal Advances in Hematology Section Body Doc Link PMC2872757 Disease Relevance 0.51 Pain Relevance 0.03
Both DMT-1 and ferroportin are regulated by the hepatically secreted defensin hepcidin, which impairs transduodenal iron transport (see below).



Regulation (regulated) of ferroportin
2) Confidence 0.01 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 0.33 Pain Relevance 0

General Comments

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