INT296385

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 12
Total Number 12
Disease Relevance 20.73
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (IDUA) carbohydrate metabolic process (IDUA) lysosome (IDUA)
Anatomy Link Frequency
upper 5
colon 2
duodenum 2
IDUA (Homo sapiens)
Pain Link Frequency Relevance Heat
nud 35 98.52 Very High Very High Very High
peptic ulcer disease 11 98.52 Very High Very High Very High
Inflammation 122 96.92 Very High Very High Very High
Piles 1 92.24 High High
Restless leg syndrome 11 89.96 High High
cva 11 85.48 High High
Arthritis 11 73.08 Quite High
cINOD 55 71.00 Quite High
aspirin 44 58.48 Quite High
Bile 11 23.76 Low Low
Disease Link Frequency Relevance Heat
Iron-deficiency Anemia 1119 100.00 Very High Very High Very High
Esophageal Disease 12 99.98 Very High Very High Very High
Hemorrhage 226 99.76 Very High Very High Very High
Obesity 11 99.66 Very High Very High Very High
Anaemia 469 99.64 Very High Very High Very High
Inflammatory Bowel Disease 264 99.64 Very High Very High Very High
Celiac Disease 141 99.50 Very High Very High Very High
Chronic Disease 100 99.24 Very High Very High Very High
Cancer 117 99.20 Very High Very High Very High
Syndrome 44 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A list of the upper and lower GI pathological conditions associated with IDA is included in Table 7.
IDA Binding (associated) of in upper associated with iron-deficiency anemia
1) Confidence 0.39 Published 2011 Journal International Journal of Medical Sciences Section Body Doc Link PMC3014590 Disease Relevance 2.32 Pain Relevance 0.09
Esophageal webs associated with IDA comprise the Plummer–Vinson syndrome.


IDA Binding (associated) of associated with esophageal disease, syndrome and iron-deficiency anemia
2) Confidence 0.28 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 2.19 Pain Relevance 0.19
A list of the upper and lower GI bleeding conditions associated with IDA is included in Table 3.
IDA Binding (associated) of in upper associated with iron-deficiency anemia and hemorrhage
3) Confidence 0.28 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.35 Pain Relevance 0
Although IDA has historically been associated with lesions in the colon, upper GI tract lesions are also commonly found in patients with IDA [4, 48].
IDA Binding (associated) of in colon associated with iron-deficiency anemia
4) Confidence 0.28 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.08 Pain Relevance 0
The utility of performing upper endoscopy in adult patients with IBD presumed to be distally confined has not been studied, however pediatric data suggests that it is useful in differentiating Crohn’s disease from ulcerative colitis [57] and therefore may be helpful in the investigation of IDA in adults with IBD as well.
IDA Binding (investigation) of in upper associated with inflammatory bowel disease, iron-deficiency anemia and disease
5) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 2.53 Pain Relevance 0.28
Red cell distribution width (RDW) has been proposed as a sensitive indicator for IDA.
IDA Binding (indicator) of associated with iron-deficiency anemia
6) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 2.01 Pain Relevance 0.15
Although IDA has historically been associated with lesions in the colon, upper GI tract lesions are also commonly found in patients with IDA [4, 48].
IDA Binding (found) of in colon associated with iron-deficiency anemia
7) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.09 Pain Relevance 0
Although anemia in IBD often involves a combination of IDA and the anemia of chronic disease (ACD), IDA remains an important contributor via: (1) decreased iron intake due to avoidance of foods that may exacerbate symptoms of IBD; (2) chronic intestinal bleeding; (3) impaired iron absorption in Crohn’s disease of the duodenum or upper jejunum; and (4) increased erythropoietin response that cannot be matched to the available iron, resulting in ineffective erythropoiesis [2].
IDA Binding (combination) of in duodenum associated with inflammatory bowel disease, anaemia, iron-deficiency anemia, hemorrhage, disease and chronic disease
8) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 2.46 Pain Relevance 0.05
Celiac disease must be considered as a cause for IDA particularly in the younger population, in particular populations with Northern European ancestry, and as previously noted can present with or without overt GI symptoms [50].
IDA Binding (cause) of associated with celiac disease and iron-deficiency anemia
9) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.84 Pain Relevance 0
Since the duodenum is the major locus of iron absorption, surgical duodenal bypass, formerly for peptic ulcer disease, and more recently as part of gastric bypass for obesity, have also been associated with the development of IDA [25, 26].
IDA Binding (associated) of in duodenum associated with peptic ulcer disease, iron-deficiency anemia, obesity and disease
10) Confidence 0.22 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.69 Pain Relevance 0.16
Although IDA has historically been associated with lesions in the colon, upper GI tract lesions are also commonly found in patients with IDA [4, 48].
IDA Binding (associated) of in upper associated with iron-deficiency anemia
11) Confidence 0.10 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.08 Pain Relevance 0
Although IDA has historically been associated with lesions in the colon, upper GI tract lesions are also commonly found in patients with IDA [4, 48].
IDA Binding (found) of in upper associated with iron-deficiency anemia
12) Confidence 0.07 Published 2010 Journal Dig Dis Sci Section Body Doc Link PMC2822907 Disease Relevance 1.09 Pain Relevance 0

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