INT296431

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gria2) endoplasmic reticulum (Gria2) plasma membrane (Gria2)
protein complex (Gria2)
Gria2 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 18 99.74 Very High Very High Very High
Pain 10 96.84 Very High Very High Very High
Lasting pain 6 85.68 High High
Neuropathic pain 4 72.24 Quite High
Inflammation 9 71.44 Quite High
Spinal cord 10 63.52 Quite High
spinal dorsal horn 7 60.64 Quite High
central sensitization 9 49.12 Quite Low
Dorsal horn neuron 6 46.44 Quite Low
Hyperalgesia 4 5.36 Low Low
Disease Link Frequency Relevance Heat
Pain 8 85.68 High High
Neuropathic Pain 4 72.24 Quite High
INFLAMMATION 9 71.44 Quite High
Motor Neuron Diseases 1 66.60 Quite High
Neurodegenerative Disease 1 65.04 Quite High
Nociception 26 57.68 Quite High
Disease 1 56.40 Quite High
Hyperalgesia 5 5.36 Low Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The phosphorylation of GluR2 subunit at Serine880 by PKC may lead to disrupt the interaction between GluR2 and GRIP and follow by GluR2 internalization.
Negative_regulation (disrupt) of GluR2 Binding (interaction) of associated with kinase c
1) Confidence 0.38 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.60 Pain Relevance 0.50

General Comments

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