INT296459

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.23
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Dlg1, Gria1) plasma membrane (Dlg1, Gria1) cytosol (Gria1)
transport (Gria1) nucleus (Dlg1) protein complex (Gria1)
Anatomy Link Frequency
synapse 3
Dlg1 (Mus musculus)
Gria1 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 27 76.80 Quite High
Spinal sensitization 3 54.84 Quite High
central sensitization 27 47.76 Quite Low
nMDA receptor 12 41.40 Quite Low
Neuropathic pain 12 17.52 Low Low
Kinase C 54 11.08 Low Low
Spinal cord 30 7.76 Low Low
Glutamate receptor 33 5.00 Very Low Very Low Very Low
Pain 30 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 27 76.80 Quite High
Hyperalgesia 15 19.60 Low Low
Neuropathic Pain 12 17.52 Low Low
Nociception 78 5.00 Very Low Very Low Very Low
INFLAMMATION 27 5.00 Very Low Very Low Very Low
Pain 24 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another PDZ domain protein, synapse-associated protein 97 (SAP 97) binds to the C-terminus of GluR1 subunit and interacts with the actin-associated protein 4.1N (which can also bind GluR1 subunit).
SAP 97 Binding (interacts) of GluR1 in synapse
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.08 Pain Relevance 0.10
Another PDZ domain protein, synapse-associated protein 97 (SAP 97) binds to the C-terminus of GluR1 subunit and interacts with the actin-associated protein 4.1N (which can also bind GluR1 subunit).
SAP 97 Binding (binds) of GluR1 in synapse
2) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.08 Pain Relevance 0.10
Another PDZ domain protein, synapse-associated protein 97 (SAP 97) binds to the C-terminus of GluR1 subunit and interacts with the actin-associated protein 4.1N (which can also bind GluR1 subunit).
SAP 97 Binding (binds) of GluR1 in synapse
3) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.08 Pain Relevance 0.10

General Comments

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