INT296471

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Rbm39) RNA binding (Rbm39) nucleus (Rbm39)
plasma membrane (Camk2a) kinase activity (Camk2a) cytoplasm (Camk2a)
Anatomy Link Frequency
spinal 2
Camk2a (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 18 100.00 Very High Very High Very High
Glutamate receptor 11 100.00 Very High Very High Very High
Pain 10 95.24 Very High Very High Very High
central sensitization 9 88.96 High High
Dorsal horn neuron 6 82.24 Quite High
Dorsal horn 6 65.64 Quite High
spinal dorsal horn 7 48.40 Quite Low
Inflammation 9 43.72 Quite Low
IPN 9 41.76 Quite Low
Hyperalgesia 4 26.00 Quite Low
Disease Link Frequency Relevance Heat
Nociception 26 99.56 Very High Very High Very High
Pain 8 95.24 Very High Very High Very High
INFLAMMATION 9 43.72 Quite Low
Inflammatory Pain 9 41.76 Quite Low
Hyperalgesia 5 26.00 Quite Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Strong noxious stimulation in the periphery tissues may activate several protein kinase cascades, such as CaMKII, PKA, PKC, and PKG, which play an important role in the phosphorylation of glutamate receptors in spinal nociceptive neurons [23,28-30].
CaMKII Regulation (role) of Phosphorylation (phosphorylation) of receptors in spinal associated with nociception, kinase c and glutamate receptor
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.27 Pain Relevance 0.47

General Comments

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