INT296544

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.02
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Hax1) endoplasmic reticulum (Hax1) nucleus (Hax1)
cytoplasm (Hax1)
Hax1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 58.16 Quite High
addiction 4 50.00 Quite Low
agonist 12 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 302 100.00 Very High Very High Very High
Stress 46 99.48 Very High Very High Very High
Disease 4 90.12 High High
Reprotox - General 1 2 86.48 High High
INFLAMMATION 4 58.16 Quite High
Sprains And Strains 22 30.20 Quite Low
Injury 6 5.00 Very Low Very Low Very Low
Liver Cancer 4 5.00 Very Low Very Low Very Low
Heat Stress Disorders 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of the Hsp genes by heat or chemical-induced oxidative stress is controlled in part by HS factor 1 (HSF1), activated under conditions in which the level of unfolded proteins increase [1-3].
Positive_regulation (activated) of HS factor 1 associated with stress and shock
1) Confidence 0.02 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 1.14 Pain Relevance 0.03
However, we cannot rule out the induction of a HSP1 cofactor secondary to PPAR?
Positive_regulation (induction) of HSP1
2) Confidence 0.02 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 0.88 Pain Relevance 0

General Comments

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