INT296622

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.52
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 8
Disease Relevance 2.24
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdh1) Golgi apparatus (Cdh1) plasma membrane (Cdh1)
cytoplasm (Cdh1)
Anatomy Link Frequency
lactotrophs 4
anterior pituitary 4
Cdh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 12 95.52 Very High Very High Very High
anesthesia 9 26.80 Quite Low
Inflammation 14 21.20 Low Low
fibrosis 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
gABA 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 108 96.60 Very High Very High Very High
Familial Adenomatous Polyposis 6 94.52 High High
Ureteral Obstruction 25 93.44 High High
Targeted Disruption 12 89.12 High High
Stress 12 82.00 Quite High
Fibrosis 20 79.60 Quite High
Hypersensitivity 9 73.08 Quite High
Aberrant Crypt Foci 29 65.40 Quite High
Colon Cancer 21 50.00 Quite Low
Sprains And Strains 1 32.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Figure 1, exogenous E-cadherin was detected in cytoplasm, which suggests that the catenin complex present was insufficient for the amount of E-cadherin that had been overexpressed.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of E-cadherin
1) Confidence 0.52 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.12 Pain Relevance 0
Thus, to confirm forced E-cadherin expression in hormone-producing cells, we transfected purified hormone-producing cells with rE-cad-IZ.
Positive_regulation (forced) of Gene_expression (expression) of E-cadherin associated with coronary artery disease
2) Confidence 0.52 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.43 Pain Relevance 0
Forced expression of E-cadherin in hormone-producing cells in the anterior pituitary of adult rats
Positive_regulation (Forced) of Gene_expression (expression) of E-cadherin in anterior pituitary
3) Confidence 0.52 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.13 Pain Relevance 0
The present study has shown that forced E-cadherin expression in lactotrophs of adult rats significantly reduced prolactin content.
Positive_regulation (forced) of Gene_expression (expression) of E-cadherin in lactotrophs
4) Confidence 0.52 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0 Pain Relevance 0
This is the first report to show forced expression of E-cadherin in rat anterior pituitary cells and its effects on hormone production.
Positive_regulation (forced) of Gene_expression (expression) of E-cadherin in anterior pituitary
5) Confidence 0.35 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.45 Pain Relevance 0
Using in situ hybridization and immunocytochemical techniques, we utilized lactotrophs to examine whether forced E-cadherin expression by gene transfection affects prolactin mRNA expression and prolactin production.


Spec (whether) Positive_regulation (forced) of Gene_expression (expression) of E-cadherin in lactotrophs
6) Confidence 0.35 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.09 Pain Relevance 0.09
-catenin, resulting in failure of ubiquitination; whereas E-cadherin mutation can cause dissociation of ?
Positive_regulation (cause) of Gene_expression (mutation) of E-cadherin
7) Confidence 0.18 Published 2010 Journal Nutr J Section Body Doc Link PMC2868780 Disease Relevance 0.31 Pain Relevance 0
Treatment with juglone preserved distal E-cadherin expression and decreased interstitial ?
Positive_regulation (distal) of Gene_expression (expression) of E-cadherin
8) Confidence 0.10 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2823698 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox