INT296724

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.29
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2rx4) transport (P2rx4) plasma membrane (P2rx4)
P2rx4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 32 94.60 High High
agonist 61 92.84 High High
Potency 55 77.24 Quite High
adenocard 5 49.40 Quite Low
ASIC 9 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Coagulation Disorder 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Pheochromocytoma 2 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Partial aggregation of rat P2X4 has been observed using EM [22].
P2X4 Spec (Partial) Binding (aggregation) of
1) Confidence 0.29 Published 2010 Journal Trends in Biochemical Sciences Section Body Doc Link PMC2824114 Disease Relevance 0 Pain Relevance 0
This supports results from mutagenesis studies at P2X2 and P2X4 receptors, where cysteine mutants of these residues were not affected by MTS reagents and were considered inaccessible to these compounds (Roberts et al., 2008).
P2X4 Binding (receptors) of
2) Confidence 0.14 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2972645 Disease Relevance 0 Pain Relevance 0.19
For the P2X4 receptor, point mutation showed residue 78 was associated with differences between rat and human receptors; for the mutant rat P2X4 Gln78Lys, the sensitivity was increased ?
P2X4 Binding (receptor) of
3) Confidence 0.14 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2972645 Disease Relevance 0 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox