INT296741

Context Info Confidence 0.08 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.44 Pain Relevance 0.13

plasma membrane (Prx) nucleus (Prx) cytoplasm (Prx)

Prx (Rattus norvegicus)

Pain Link Frequency Relevance Heat cytokine 7 92.52 Inflammation 8 92.16 metalloproteinase 5 5.00 ischemia 2 5.00 iatrogenic 1 5.00 anesthesia 1 5.00 fibrosis 1 5.00 Inflammatory response 1 5.00 chemokine 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Lung Injury 38 96.64 INFLAMMATION 9 92.16 Endotoxemia 1 88.40 Emergencies 2 12.68 Adult Respiratory Distress Syndrome 20 5.00 Injury 5 5.00 Adhesions 4 5.00 Stress 3 5.00 Pressure And Volume Under Development 2 5.00 Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our results indicate that treatment with doxycycline prevents a decrease in levels of Prx II; therefore the antioxidative capacity of pulmonary tissue might be increased, which could result in lower susceptibility to ventilation induced damage.

Negative_regulation (prevents) of Negative_regulation (decrease) of Prx

1) Confidence 0.08 Published 2010 Journal Proteome Sci Section Body Doc Link PMC2824689 Disease Relevance 0.44 Pain Relevance 0.13

General Comments

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