INT296787

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr9) signal transduction (Tlr9) endoplasmic reticulum (Tlr9)
plasma membrane (Tlr9) intracellular (Tlr9) lysosome (Tlr9)
Tbrs1 (Mus musculus)
Tlr9 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 60 99.84 Very High Very High Very High
Inflammation 8 98.12 Very High Very High Very High
Opioid 18 81.48 Quite High
cytokine 7 77.92 Quite High
Inflammatory response 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 44 100.00 Very High Very High Very High
INFLAMMATION 10 98.12 Very High Very High Very High
Apoptosis 37 93.28 High High
Infection 31 92.00 High High
Targeted Disruption 20 72.32 Quite High
Drug Dependence 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine and M. tuberculosis significantly induced the expression of Toll-like receptor 9 (TLR9), a key mediator of innate immunity and inflammation.
tuberculosis Positive_regulation (induced) of Gene_expression (expression) of Toll-like receptor 9 associated with mycobacterial infection, inflammation and morphine
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2824811 Disease Relevance 1.37 Pain Relevance 0.78

General Comments

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