INT296788

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr9) signal transduction (Tlr9) endoplasmic reticulum (Tlr9)
plasma membrane (Tlr9) intracellular (Tlr9) lysosome (Tlr9)
Tlr9 (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 60 99.78 Very High Very High Very High
Opioid 18 93.16 High High
drug abuse 1 89.04 High High
methadone 1 50.32 Quite High
agonist 1 11.68 Low Low
Inflammation 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 44 93.96 High High
Drug Dependence 4 89.04 High High
Infection 31 88.64 High High
Targeted Disruption 20 75.16 Quite High
Disease Susceptibility 1 74.08 Quite High
Sprains And Strains 3 63.28 Quite High
Apoptosis 37 50.00 Quite Low
Emergencies 1 43.52 Quite Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, morphine and H37Ra-induced TNF, IL-1, and IL-6 production appears to be controlled by TLR9 (Fig. 2).
TLR9 Spec (appears) Regulation (controlled) of Positive_regulation (induced) of IL-1 associated with morphine
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824811 Disease Relevance 1.37 Pain Relevance 0.77

General Comments

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