INT296806

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.73
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn5a) plasma membrane (Scn5a) transmembrane transport (Scn5a)
Scn5a (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 132 99.98 Very High Very High Very High
Action potential 36 92.64 High High
nav1.3 12 54.00 Quite High
anesthesia 6 47.04 Quite Low
imagery 30 5.00 Very Low Very Low Very Low
addiction 12 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disorder Under Development 18 99.98 Very High Very High Very High
Fibrosis 114 94.68 High High
Arrhythmias 2 Under Development 162 92.52 High High
Targeted Disruption 24 87.08 High High
Heart Rate Under Development 30 85.24 High High
Aging 60 80.84 Quite High
Stress 6 77.40 Quite High
Disease 24 75.00 Quite High
Heart Arrhythmia 96 58.56 Quite High
Sprains And Strains 6 58.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phenotype severity in Scn5a+/?
Positive_regulation (severity) of Gene_expression (severity) of Scn5a
1) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.30 Pain Relevance 0
Scn5a transcript levels were similar in both groups of Scn5a+/?
Positive_regulation (groups) of Gene_expression (/) of Scn5a
2) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.16 Pain Relevance 0.05
Semi-quantitative assessment of cardiac fibrosis led to mean scores of 1.88±0.40 in Scn5a+/?
Positive_regulation (led) of Gene_expression (/) of Scn5a associated with fibrosis and cardiovascular disorder under development
3) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 1.12 Pain Relevance 0.30
The reason for increased expression of Nav1.5 protein in mice with a mild phenotype is as yet unknown.
Positive_regulation (increased) of Gene_expression (expression) of Nav1.5 protein
4) Confidence 0.47 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.21 Pain Relevance 0
mice had similar Nav1.5 mRNA but higher Nav1.5 protein expression, and moderately larger INa current than severely affected Scn5a+/?
Positive_regulation (higher) of Gene_expression (expression) of Nav1.5 protein
5) Confidence 0.47 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2824822 Disease Relevance 0.62 Pain Relevance 0.10
There was a progressive increase in QRS interval with age in WT and Scn5a+/?
Positive_regulation (increase) of Gene_expression (/) of Scn5a
6) Confidence 0.44 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824822 Disease Relevance 0.31 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox