INT296857

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 14
Disease Relevance 9.46
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (B4galnt2) Golgi apparatus (B4galnt2)
Anatomy Link Frequency
neurons 3
brains 2
bands 1
B4galnt2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 14 95.56 Very High Very High Very High
Pyramidal cell 84 93.32 High High
Hippocampus 70 77.76 Quite High
Immobilon 14 75.28 Quite High
Neurobehavioral 14 69.44 Quite High
Limbic system 42 5.00 Very Low Very Low Very Low
anesthesia 14 5.00 Very Low Very Low Very Low
Locus ceruleus 14 5.00 Very Low Very Low Very Low
Substantia nigra 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 826 100.00 Very High Very High Very High
Disease 770 99.12 Very High Very High Very High
Targeted Disruption 140 98.36 Very High Very High Very High
Aging 28 96.00 Very High Very High Very High
Movement Disorders 28 95.48 Very High Very High Very High
Dementia 126 94.56 High High
Neurodegenerative Disease 126 89.68 High High
Lewy Body Disease 84 75.00 Quite High
Infection 70 24.40 Low Low
Pick Disease Of The Brain 42 20.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared to the unimpaired neurons in the control cases, in DLB brains, mTor and LC3 immunoreactivity were more abundant in neurons displaying ?
Gene_expression (brains) of DLB in neurons associated with parkinson's disease
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.76 Pain Relevance 0.03
Compared to non-demented controls and AD cases, levels of mTor and phosphorylated-mTor (p-mTor) were elevated in the brains of DLB cases (Figure 1A, C).
Gene_expression (cases) of DLB in brains associated with parkinson's disease and disease
2) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.77 Pain Relevance 0
The formation of such abnormal AV-like structures in DLB and ?
Gene_expression (structures) of DLB associated with parkinson's disease
3) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.55 Pain Relevance 0
Consistent with previous studies [34], levels of Beclin-1 in the membrane fractions were reduced in the AD cases compared to non-demented controls and DLB, however no differences in Beclin-1 levels were detected between non-demented controls and DLB cases (Figure 1A, C).
Gene_expression (detected) of DLB associated with parkinson's disease and disease
4) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.92 Pain Relevance 0.07
Consistent with previous studies [34], levels of Beclin-1 in the membrane fractions were reduced in the AD cases compared to non-demented controls and DLB, however no differences in Beclin-1 levels were detected between non-demented controls and DLB cases (Figure 1A, C).
Gene_expression (detected) of DLB associated with parkinson's disease and disease
5) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.92 Pain Relevance 0.04
Since alterations in the autophagy pathway in DLB and in ?
Gene_expression (pathway) of DLB associated with parkinson's disease
6) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.20 Pain Relevance 0.03
Since in addition to the increase in mTor, we also observed a reduction in Atg7 levels in DLB and ?
Gene_expression (levels) of DLB associated with parkinson's disease
7) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.38 Pain Relevance 0.10
Briefly, as previously described [42], vibratome sections from control, DLB brains and ?
Gene_expression (brains) of DLB in brains associated with parkinson's disease
8) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.10 Pain Relevance 0.12
In DLB brains, mTor was more abundant in neurons displaying ?
Gene_expression (brains) of DLB in neurons associated with parkinson's disease
9) Confidence 0.07 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2824828 Disease Relevance 1.50 Pain Relevance 0
Supporting this possibility, the present study also showed that the cortical neurons in DLB cases and in ?
Gene_expression (cases) of DLB in neurons associated with parkinson's disease
10) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.60 Pain Relevance 0
The study included a total of 24 cases (Table 1); of them, 6 were non-demented controls, 12 were DLB cases and the other 6 were AD cases.
Gene_expression (cases) of DLB associated with parkinson's disease and disease
11) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.46 Pain Relevance 0.03
-syn and neurodegeneration in DLB cases and ?
Gene_expression (cases) of DLB associated with parkinson's disease
12) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.33 Pain Relevance 0.03
Remarkably, we found that in DLB cases and in ?
Gene_expression (cases) of DLB associated with parkinson's disease
13) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 1.13 Pain Relevance 0
By immunoblot analysis, in the DLB cases there was an increase in immunoreactive bands representing monomeric and aggregated ?
Gene_expression (cases) of DLB in bands associated with parkinson's disease
14) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.84 Pain Relevance 0.08

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