INT296875

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 3.53
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

vesicle-mediated transport (AHI1) cytoskeleton (AHI1) cilium (AHI1)
cytoplasm (AHI1)
AHI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 18 94.12 High High
Central nervous system 4 76.16 Quite High
tramadol 1 47.92 Quite Low
Gabapentin 1 47.12 Quite Low
Inflammation 15 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apnoea 279 100.00 Very High Very High Very High
Sleep Disorders 40 100.00 Very High Very High Very High
Obesity 95 99.76 Very High Very High Very High
Prediabetic State 54 99.16 Very High Very High Very High
Diabetes Mellitus 48 98.68 Very High Very High Very High
Sleep Apnea Syndromes 3 79.28 Quite High
Weight Gain 1 52.24 Quite High
Death 3 34.16 Quite Low
Overdose 1 24.72 Low Low
Neurological Disease 1 24.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The other patient was a 58-year-old man (BMI, 32) whose AHI increased from 5/h and 11/h on two consecutive nights to 24/h and 45/h following the administration of SXB.
Positive_regulation (increased) of AHI associated with obesity
1) Confidence 0.15 Published 2009 Journal Sleep Breath Section Body Doc Link PMC2824842 Disease Relevance 1.30 Pain Relevance 0.11
In a model adjusting for sex, race, age, and BMI, both increases in AHI and the presence of prediabetes/diabetes were associated with reductions in HOMA-IS (P = 0.003) in the entire cohort.
Positive_regulation (increases) of AHI associated with diabetes mellitus and prediabetic state
2) Confidence 0.04 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.50 Pain Relevance 0
Even after adjusting for sex and BMI, the increases in AHI in subjects with NGM were associated with increases in HOMA-B (P < 0.001), HOMA-IR (P < 0.001), and insulin levels (P < 0.001).
Positive_regulation (increases) of AHI
3) Confidence 0.03 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.30 Pain Relevance 0
Both increases in apnea-hypopnea index (AHI) and the presence of prediabetes/diabetes were associated with reductions in HOMA-IS in the entire cohort even after adjustment for sex, race, age, and BMI (P = 0.003).
Positive_regulation (increases) of AHI associated with apnoea, diabetes mellitus, prediabetic state and sleep disorders
4) Confidence 0.03 Published 2010 Journal Cardiovasc Diabetol Section Abstract Doc Link PMC3002325 Disease Relevance 1.43 Pain Relevance 0.05

General Comments

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