INT296911

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casq1) Golgi apparatus (Casq1) molecular_function (Casq1)
response to stress (Casq1) cytoplasm (Casq1)
Casq1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 8 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Morphine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 208 99.84 Very High Very High Very High
Stress 24 69.04 Quite High
Apoptosis 100 66.96 Quite High
Shock 4 55.44 Quite High
Death 16 48.72 Quite Low
Myocardial Infarction 16 43.32 Quite Low
Injury 64 27.12 Quite Low
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
B-cell Acute Lymphoblastic Leukemia 4 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results showed increased expression of calsequestrin in hypoxia-reoxygenation condition (p < 0.05), but there was no significant change in response to exposure to thiopental.
Positive_regulation (increased) of Gene_expression (expression) of calsequestrin associated with hypoxia
1) Confidence 0.09 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.29 Pain Relevance 0
Considering that calsequestrin overexpression increases SR Ca2+ content by inhibition of RyRs,42 calsequestrin overexpression is also likely to contribute to intracellular Ca2+ overload.
Positive_regulation (overexpression) of Gene_expression (overexpression) of calsequestrin
2) Confidence 0.09 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.44 Pain Relevance 0
Considering that calsequestrin overexpression increases SR Ca2+ content by inhibition of RyRs,42 calsequestrin overexpression is also likely to contribute to intracellular Ca2+ overload.
Positive_regulation (overexpression) of Gene_expression (overexpression) of calsequestrin
3) Confidence 0.09 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.38 Pain Relevance 0
Considering that calsequestrin overexpression increases SR Ca2+ content by inhibition of RyRs,42 calsequestrin overexpression is also likely to contribute to intracellular Ca2+ overload.
Positive_regulation (increases) of Gene_expression (overexpression) of calsequestrin
4) Confidence 0.07 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.38 Pain Relevance 0

General Comments

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