INT296927

Context Info Confidence 0.10 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0

mitochondrion (Casq1) Golgi apparatus (Casq1) molecular_function (Casq1) response to stress (Casq1) cytoplasm (Casq1)

Anatomy Link Frequency lumen 1 Casq1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat ischemia 2 5.00 tolerance 1 5.00 Glutamate 1 5.00 Inflammation 1 5.00 Morphine 1 5.00

Disease Link Frequency Relevance Heat Hypoxia 52 95.52 Stress 6 52.00 Apoptosis 25 49.92 Shock 1 38.40 Myocardial Infarction 4 36.92 Death 4 31.68 Injury 16 20.72 Cv Unclassified Under Development 2 5.00 B-cell Acute Lymphoblastic Leukemia 1 5.00 Repression 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Calsequestrin is located in the SR lumen and reduces ryanodine receptor activity (RyRs: Ca2+ release channels).

Localization (located) of Calsequestrin in lumen

1) Confidence 0.10 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.32 Pain Relevance 0

General Comments

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